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Bette skrev 2009-09-16 15:45:56 följande:
GrattisEpigenetics - The Importance of the Birth Mother
An article about epigenetics that referred to the influence of the birth
mother on the genetic make up of a child born from donor eggs. ?..
Genes must be ?expressed? within an individual in order to have an
effect.
The same gene or genes can express in a number of different ways depending
upon the environment. A gene can remain ?silent? or unexpressed; it can be
expressed strongly; it can be expressed weakly, and so on. There is also an
entire field of study called ?imprinting? having to do with which gene you
?activate,? the copy you received from your mother, or the copy you
received from your father.
The field of epigenetics studies these phenomenon, and popular journalism
is just starting to write about it. While the Human Genome Project was
still underway, we usually heard genes referred to as ?the Bible? of the
human being, as a kind of absolute truth concerning the fundamental nature
of the individual.
That is now changing.
In a donor egg pregnancy, the pregnant woman?s womb is the environment. It
is her genes, not the donor?s, that determine the expression of the
donor-egg baby?s genes.
A donor egg baby gets her genes from the donor; she gets the
?instructions? on the expression of those genes from the woman who carries
her to term.
This means that a donor egg baby has 3 biological parents: a father, the
egg donor, and the woman who carries the pregnancy.
The child who is born would have been a physically & no doubt emotionally
different person if carried by his genetic mother.
In horse breeding for example, it?s not uncommon to implant a pony embryo
into the womb of a horse.
The foals that result, are different from normal ponies. They?re bigger.
These animals? genotype ? their genes ? are the same as a pony?s, but their
phenotype ? what their genes actually look like in the living animal ? is
different.
The implication of epigenetics is that the child inherits characteristics
from the woman who carries the child even if the original DNA comes from a
donor egg. In other words the birth mother influences what the child is
like at a genetic level - it IS her child."